The Best Hotels and Places to Stay Along Nelson County’s Route 151 Wine and Brewery Trail

Greetings from the Blue Ridge Mountains! I’m your friendly Route 151 local guide, and I’ve lived in Nelson County for years. I’ve spent more weekends than I can count hiking the Blue Ridge, sipping bold reds at Veritas Vineyards, and catching bluegrass shows at Blue Mountain Brewery. If you're planning a visit to this gorgeous part of Virginia, you're in for a treat—especially if you're exploring the 151 Wine and Brewery Trail.

The trail is famous for its relaxed mountain beauty, top-notch wineries, breweries, cideries, and cozy restaurants. And whether you’re here for a girls’ weekend, romantic escape, or group getaway, where you stay can seriously elevate the whole experience.

Here are my favorite hotels, inns, and vacation rentals right along (or just off) the Route 151 trail. Yes, I’ve visited (or stayed at) every single one, and I’m not afraid to play favorites. Let’s dive in!

Afton Mountain Inn – Luxury 10-Acre Resort with Pool, Hot Tubs & Fire Pits

Address: 10221 Rockfish Valley Hwy, Afton, VA
Website: aftoninn.com
Price: From $179 per night

This boutique inn is a true hidden gem. Tucked right off Route 151, Afton Mountain Inn is a lovingly restored 1848 farmhouse on 10 peaceful acres. It’s got a resort-style pool, two hot tubs, porch swings, fire pits, and even a private trail by a creek. I brought my parents here once for a wine weekend and they spent half the trip just lounging by the pool and soaking in the views.

With six luxurious suites and a stylish two-bedroom villa, it’s ideal for couples, friend groups, or wedding guests. You're within minutes of some of the best spots on the trail: Veritas Vineyards, Bold Rock Cidery, Blue Mountain Brewery, and Silverback Distillery, just to name a few.

What makes Afton Mountain Inn special

• Resort-style pool and cabanas

• Two hot tubs and three fire pits for evening hangouts

• Complimentary snacks and ice cream

• Surrounded by mountain views, a creekside nature trail, and wildflower fields

• Just minutes from the heart of Route 151’s best wineries and breweries

Why Stay Here

Afton Mountain Inn is for people who want the charm of a boutique inn with the amenities of a mini resort. It’s peaceful and romantic, yet so close to all the action. You’ll be sipping wine one minute and soaking in a hot tub the next.

Afton Farmhouse – Family-Friendly Mountain Getaway with Fire Pit and Giant Kitchen

Address: 161 Avon Rd, Afton, VA
Website: aftonfarmhouse.com
Price: From $299 per night (sleeps up to 11)

This is the kind of place where big family memories get made. With space for 11 guests, a bunk room, a full kitchen, and a foosball table, Afton Farmhouse is your classic countryside retreat. The kids will go nuts for the soccer goals and playground, and the adults will love the long porch views of the Blue Ridge and the nearby wineries.

You're right in the heart of the 151 trail here—Flying Fox Vineyard is just up the road, Devils Backbone and Hill Top Berry Farm are close by, and Blue Toad Cidery is a short drive. It’s also right next door to WildManDan Brewery, a quirky, welcoming nano-brewery with small-batch beers and local character. Stock the fridge, open a local bottle, and enjoy a little slice of mountain life.

What makes Afton Farmhouse special

• Sleeps 11 comfortably with a layout made for gathering

• Huge kitchen and dining area, perfect for family-style meals

• Yard games, fire pit, play structure, and backyard with mountain views

• Right off Route 151 near top-rated wineries and breweries

Why Stay Here

If you’ve got kids, pets, friends, or extended family in tow, Afton Farmhouse is the move. It’s a relaxing, welcoming home base surrounded by vineyard views and plenty of space to unwind. Pour some rosé and let the kids chase fireflies—it’s that kind of place.

The Farmhouse at Veritas – Elegant Vineyard Stay with Gourmet Dining

Address: 72 Saddleback Farm, Afton, VA
Website: veritasfarmhouse.com
Price: From $395 per night

If you're dreaming of waking up in the middle of a vineyard, this is it. The Farmhouse at Veritas sits right on the grounds of Veritas Vineyards & Winery, one of my all-time favorite stops on the Nelson 151 trail. It’s elegant and historic, with seven beautifully appointed guest rooms and a chef-driven breakfast each morning.

Every time I stay here, I feel like I’m in a wine country dream. You can book a five-course wine-paired dinner right next door at The Tasting Room, then walk home under the stars. It’s romantic, peaceful, and incredibly refined.

What makes The Farmhouse at Veritas special

• Located on-site at a working vineyard and winery

• Gourmet breakfasts and wine-paired dinners available

• Gorgeous, historic home with seven upscale guest rooms

• Private access to some of the best wine in the state

Why Stay Here

If you’re here to celebrate something—or just treat yourself—this is your place. Perfect for romantic weekends, anniversaries, or a luxurious wine country escape.

Afton Clubhouse – Huge Open Floor plan Home with Hot Tub, Fire Pit, and Games

Address: 161 Avon Rd, Afton, VA
Website: aftonclubhouse.com
Price: From $279 per night (sleeps up to 8)

Once an art gallery, now a bright and stylish vacation home, Afton Clubhouse is perfect for couples or small groups who want a playful, design-forward place to stay. It’s got three bedrooms, a shuffleboard table, indoor basketball, outdoor ping pong, a hot tub, a fire pit, and plenty of open space to hang out and laugh together.

And when you’re ready to explore, you’re in luck—Starr Hill Brewery, Valley Road Vineyards, and Hazy Mountain Winery are just a few minutes away. Even better, it’s right next door to Wild Man Dan’s Brewery, a small but mighty local favorite where you can grab a pint just steps from your door. I stayed at Afon Clubhouse during the peak of fall color season and we hit three wineries and ended up at Wild Man Dan’s Brewery before walking home for a soak in the hot tub. Heaven.

What makes Afton Clubhouse special

• Fun amenities like indoor basketball, shuffleboard, and a hot tub

• Chic, open layout designed for good vibes and great company

• Perfectly placed along Route 151 for a quick hop between tastings

• Ideal for weekend getaways with friends

Why Stay Here

It’s cozy, it’s stylish, and it’s packed with fun things to do. Afton Clubhouse is for groups who want to relax and celebrate—with amazing drinks, fresh mountain air, and a hot tub under the stars.

Basecamp 151 – Sleek, Budget-Friendly Stay Right on the Trail

Address: 999 Critzer Shop Rd, Afton, VA
Website: basecamp151.com
Price: From $159 per night

Basecamp 151 is clean, modern, and incredibly convenient. Located in the heart of Route 151, it’s a smart and affordable place to stay if you're planning to hit as many wineries and breweries as possible.

The rooms are sleek and minimal, but cozy—and there’s even a shared lounge area to hang out and plan your tasting route. I stayed here once during a girls’ weekend and we knocked out five spots in one afternoon without ever getting off Route 151.

What makes Basecamp 151 special

• Excellent value and modern design

• Walkable or bikeable to the northern wineries on 151

• Great launch point for exploring the full trail

• Simple and stylish without the frills

Why Stay Here

Basecamp 151 is perfect for folks who want to spend more time out tasting and less time worrying about logistics. It’s practical, comfortable, and perfectly placed.

Glenbrae – Romantic Scottish-Style Manor with Epic Mountain Views

Address: Private Drive in Afton, VA
Website: glenbraeva.com
Price: From $375 per night (Sleeps up to 10)

This Scotland-inspired mountain estate is the newest showstopper on the Route 151 scene. Set high on a hillside with sweeping Blue Ridge views, Glenbrae feels like your own private castle in the sky. The interiors are jaw-droppingly elegant—think deep green walls, cozy plaid throws, a moody cocktail bar, and epic soaking tubs.

You’re just a few minutes from Septenary Winery, Hazy Mountain Vineyards, and Cardinal Point Vineyard—but you may never want to leave the house. Every detail has been thoughtfully curated for comfort and style.

What makes Glenbrae special

• Dramatic mountain views and Scottish manor vibes

• Custom interiors with high-end finishes and vintage charm

• Romantic soaking tubs, luxe furnishings, and a private deck

• Minutes from top 151 wineries, but completely tucked away

Why Stay Here

It’s where to stay when you want something cinematic and serene. Glenbrae is ideal for couples, writers, design lovers, or anyone looking for inspiration between sips.

Afton Awaits – Modern House in the Woods with Stunning Mountain Views

Address: Private Drive in Afton, VA
Website: aftonawaits.com
Price: From $295 per night (Sleeps up to 6)

Afton Awaits is exactly what its name promises: a modern mountain retreat that’s waiting to welcome you. The decor is a mix of clean Scandinavian lines and warm Appalachian wood, with huge windows that look out over the mountains.

You’ll feel like you’re tucked into nature, but you’re just around the corner from Silverback Distillery, Blue Mountain Brewery, and Hill Top Berry Farm. I stayed here with my extended family and we spent the weekend hopping between tastings and curling up in front of the fireplace.

What makes Afton Awaits special

• Sleek, modern home with panoramic views

• Perfectly located for mid-trail tasting adventures

• Fireplace, big windows, and a peaceful, romantic setting

• Feels off the grid, but close to everything

Why Stay Here

It’s the perfect blend of modern comfort and mountain calm. Afton Awaits is great for couples or larger groups who want something beautiful, thoughtful, and right in the heart of 151.

Final Thoughts

The Route 151 Wine and Brewery Trail is one of Virginia’s best-kept secrets—and the places you stay along the way can make the whole experience even more magical. From luxury inns and scenic estates to fun-filled vacation homes and sleek trail-side stops, there's truly something for everyone.

My advice? Slow down. Savor the views. Taste everything. And pick a place to stay that gives you room to breathe, space to connect, and that unmistakable Blue Ridge vibe.

See you out there on the trail!